Genome Editing and Engineering (English)

   Saturday, September 05, 2026   

Starting a new Lecture Notes Series on Genome Editing and Engineering

Youtube Lecture Playlist Credits 

Channel Name: NPTEL IIT Guwahati

So Let Us Start to This Journey of Learning 

Genome Editing and Engineering By Lecture Notes together!

Lecture 1: Genome Editing and Engineering

Lecture 2: Lec 1: Introduction :Genes and Genome Organization

Lecture 3: Lec 2: History and Basics of Genetic Engineering

Lecture 4: Lec 3: Advantages and Limitations of Genetic Engineering

Lecture 5: Lec 4: Breakage of Genomic DNA

Lecture 6: Lec 5: Repair of Genomic DNA

Lecture 7: Lec 6: Homologous and non homologous recombination

Lecture 8: Lec 7: Site specific recombination

Lecture 9: Lec 8: Targeted genetic modification - I

Lecture 10: Lec 9: Targeted genetic modification - II

Lecture 11: Lec 10: Basics of Zinc Finger Nucleases

Lecture 12: Lec 11: Design of Zinc Finger Nucleases for genome editing

Lecture 13: Lec 12: Applications of Zinc Finger Nucleases - PART A

Lecture 14: Lec 13: Applications of Zinc Finger Nucleases - PART B

Lecture 15: Lec 14: Basics of TALEN - PART A

Lecture 16: Lec 15: Basics of TALEN - PART B

Lecture 17: Lec 16: Design of TALEN for genome editing - PART A

Lecture 18: Lec 17: Design of TALEN for genome editing - PART B

Lecture 19: Lec 18: Application of TALEN - Part A

Lecture 20: Lec 19: Application of TALEN - Part B

Lecture 21: Lec 20: CRISPR system in bacteria - Part A

Lecture 22: Lec 21: CRISPR system in bacteria - Part B

Lecture 23: Lec 22: CRISPR/Cas9 in Genome Editing - Part A

Lecture 24: Lec 23: CRISPR/Cas9 in Genome Editing - Part B

Lecture 25: Lec 24: Applications of CRISPR/Cas9 Part A

Lecture 26: Lec 25: Applications of CRISPR/Cas9 Part B

Lecture 27: Lec 26: Computational Resources for CRISPR / Cas - Part A

Lecture 28: Lec 27: Computational Resources for CRISPR / Cas - Part B

Lecture 29: Lec 28: Human cell engineering in diseases : Thalassemia - Part A

Lecture 30: Lec 29: Human cell engineering in diseases : Thalassemia - Part B

Lecture 31: Lec 30: Human cell engineering in diseases : Severe combined immunodeficiency (SCID) - Part A

Lecture 32: Lec 31: Human cell engineering in diseases : Severe combined immunodeficiency (SCID) - Part B

Lecture 33: Lec 32: Human cell engineering in diseases : Hemophilia - Part A

Lecture 34: Lec 33: Human cell engineering in diseases : Hemophilia - Part B

Lecture 35: Lec 34: Animal models - Part A

Lecture 36: Lec 35: Animal models - Part B

Lecture 37: Lec 36: iPSc models - Part A

Lecture 38: Lec 37: iPSc models - Part B

Lecture 39: Lec 38: Cancer disease models - Part A

Lecture 40: Lec 39: Cancer disease models - Part B

Lecture 41: Lec 40: Engineered immune cells for Cancer therapy (I) - Part A

Lecture 42: Lec 41: Engineered immune cells for Cancer therapy (I) - Part B

Lecture 43: Lec 42: Engineered immune cells for Cancer therapy (II) - Part A

Lecture 44: Lec 43: Engineered immune cells for Cancer therapy (II) - Part B

Lecture 45: Lec 44: History and Basics - Part A

Lecture 46: Lec 45: History and Basics - Part B

Lecture 47: Lec 46: Genome editing and personalized therapy

Lecture 48: Lec 47: Bioethics and Biosafety - Part A

Lecture 49: Lec 48: Bioethics and Biosafety - Part B

Lecture 50: Lec 49: Regulatory issues in Genome Editing

Lecture 51: Lec 48: Bioethics and Biosafety - Part B